Lupus: Criteria for Diagnosis
Lupus: Criteria for DiagnosisSkip to the navigationTopic Overview The following criteria are used to distinguish
lupus (systemic lupus erythematosus, or SLE) from
other
autoimmune and rheumatic diseases. A
person with 4 of these 11 conditions can be classified as having lupus. These
conditions may be present all at once, or they may appear in succession over a
period of time.footnote 1 - Butterfly (malar) rash on cheeks
- Rash
on face, arms, neck, torso (discoid rash)
- Skin rashes that result
from exposure to sunlight or
ultraviolet light (photosensitivity)
- Mouth
or nasal sores (ulcers), usually painless
- Joint swelling,
stiffness, pain involving two or more joints (arthritis)
- Inflammation of the membranes
surrounding the lungs (pleuritis) or
heart (pericarditis)
- Abnormalities in urine, such as increased protein or
clumps of red blood cells or kidney cells, called cell casts
- Nervous system problems, such as
seizures or
psychosis, without known cause
- Problems
with the blood, such as reduced numbers of red blood cells (anemia), platelets, or white blood
cells
- Laboratory tests showing increased
autoimmune activity (antibodies against normal
tissue)
- Positive antinuclear antibody (ANA) test
ReferencesCitations- Crow MK (2016). Systemic lupus erythematosus. In L Goldman, A Shafer, eds., Goldman-Cecil Medicine, 24th ed., vol. 2, pp. 1769-1777. Philadelphia: Saunders.
CreditsByHealthwise Staff
Primary Medical ReviewerAnne C. Poinier, MD - Internal Medicine
Martin J. Gabica, MD - Family Medicine
E. Gregory Thompson, MD - Internal Medicine
Specialist Medical ReviewerNancy Ann Shadick, MD, MPH - Internal Medicine, Rheumatology Current as ofOctober 31, 2016 Current as of:
October 31, 2016 Crow MK (2016). Systemic lupus erythematosus. In L Goldman, A Shafer, eds., Goldman-Cecil Medicine, 24th ed., vol. 2, pp. 1769-1777. Philadelphia: Saunders. Last modified on: 8 September 2017
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